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26.05.2016

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Adeno-Associated Virus titer and aggregation characterization

We recently published our application note, “Adeno-Associated Virus titer and aggregation characterization“, which discusses a new NanoSight method that allows the visualization and therefore analysis of viruses smaller than what was previously possible to measure.  T...

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25.05.2016

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Upcoming Webinar: John Carpenter discusses silicone oil-induced protein aggregation and immunogenicity

We’re lucky here at Malvern Instruments to have a large number of customers and collaborators who are happy to share their experience of using our technologies for an ever-expanding range of applications.  Some co-write peer-reviewed papers with us, others help us create ap...

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24.05.2016

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Recap of PEGS Boston, the Essential Protein Engineering Summit

I recently had the pleasure of participating in PEGS Boston, the 12th anniversary meeting organized by Cambridge Healthtech Institute (CHI).  The meeting was at Seaport World Trade Center in Boston, Massachusetts, from April 25-29, 2016. I was joined by my Malvern colleagues Bob ...

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19.05.2016

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Malvern at Analytica 2016!

Lesen Sie diesen Blog auf Deutsch GREAT TO MEET YOU! What really matters? Building relationships From the point of view of an exhibitor, exhibitions often mean long days, lots of coffee and sometimes blistered feet if you happen to be wearing the wrong shoes.  Despite this, they ...

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17.05.2016

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The Kinexus gets a manicure…

Over the last few years, the nail polish industry has really opened up its beauty box of tricks, and on the market today, to name but a few, we see nail polishes with “magnetic, gel, matte, glitter, crackle, stamping, quick-dry, caviar, sponge, color changing, leather and sandy” ...

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16.05.2016

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Malvern at AAPS NBC: Zetasize your formulation, VLP, vaccine, and nanoparticle

From nanoemulsions, nanosuspensions, vaccines and adjuvants to drug formulation and release development, this year’s American Association of Pharmaceutical Scientists (AAPS) National Biotech Conference has the strapline: “Advancing health through innovation in biother...

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12.05.2016

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Recap of the 5th International Symposium on Higher Order Structure of Protein Therapeutics

I had the pleasure of participating in the 5th International Symposium on Higher Order Structure of Protein Therapeutics, also known as HOS2016, sponsored by CASSS. The meeting was at the Renaissance Hotel in Long Beach, California April 11-13, 2016. I was joined by my Malvern co...

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10.05.2016

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Missed our April webinars? Catch up here…

Here is another exciting month with some really subject that will be discussed this month again. Here is the full program for May. Register now! As per last month I have compiled the latest list of our On Demand webinars. Just click and choose your favorite subject.    ...

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05.05.2016

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Water treatment – a better way than jar testing?

Water is at the foundation of life. Thus for humans H2O is of critical importance and most directly so for drinking water. In order to prepare water for safe consumption, water treatment procedures have been developed and improved to provide a reliable source of healthy drinking ...

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04.05.2016

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Bioseminar Series 2016 – Addressing Immunogenic Risk

Hello! First I’d like to quickly introduce myself. I just joined Malvern Instruments as a Digital Marketing Specialist based in Westborough, MA, USA office. My main role is to help driving the online and email marketing campaigns. We are pleased to announce our 2016 Bioseminar Se...

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03.05.2016

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Malvern’s Top Content Q1 2016

Malvern Instruments produces a huge array of content, from beginner’s guides to advanced education, all of which is free to access on the Resource Center at Malvern.com. Malvern’s content is available in a variety of formats, and to help explain what these different formats are, ...

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28.04.2016

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Site requirements for the Zetasizer

You are seriously considering ordering a Zetasizer. An excellent choice! A typical email we often receive at this point is: “What are the site requirements for the system?”     The Malvern Zetasizer is a compact benchtop measurement system which requires little space on...

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26.04.2016

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Malvern at Powtech 2016!

Recipe for a successful exhibition: good shoes, good coffee and – most importantly – good conversation! Read this blog in German An exhibition is the perfect platform to discover new products and innovations and to network with key people in related industries who hav...

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21.04.2016

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Elucidation of aggregation kinetics with DLS

“I’m looking to study the aggregation kinetics of my nanoparticles using the Zetasizer Nano ZS. Is there a way to make time-resolved size measurements using this instrument?” The Zetasizer has become a fairly standard sizing tool for nanoparticles, as the size and the size ...

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19.04.2016

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British Science Week 2016

We recently took part in events to celebrate British Science Week, which this year took place over a ten day period from 11th – 20th March. British Science Week is an annual celebration of science, technology, engineering and maths (STEM subjects), with events taking place across...

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14.04.2016

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Team Malvern making moves for charity

We have a wonderful team here at Malvern Instruments, full of people who are constantly looking for ways to give back to the community on a local or even global scale.  And apparently, we are a particularly sporty lot as well, with lots of Malvernites setting out on sponsored run...

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12.04.2016

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Using a Rotational Rheometer for High Shear Rate Measurements

Recently I have been showing some of our rotational rheometer customers how to make high shear measurements on their instruments. This highlights some of the hard to define measurement constraints that rheometer users can have when pushing the practical limits of the instrument. ...

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07.04.2016

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Malvern sponsors 9th Annual Proteins and Antibodies Congress in London

We are proud to be sponsoring the 9th Annual Proteins and Antibodies Congress, to be held at the Novotel London West, UK on 18th and 19th April 2016.  Malvern MicroCal’s Principal Scientist, Dr. Natalia Markova, will be chairing the Protein Expression and Characterization Stream ...

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05.04.2016

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Missed our March webinars? Catch up here…

How time flies! Spring is here already! Just for you I have collated the latest list of our On Demand webinars. Just click and choose your favorite subject. I also listed all our upcoming webinars for April. You can register for free and if you can’t attend, we’ll sen...

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25.03.2016

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Hunting for the Perfect Easter Egg

In the UK we are about to celebrate Easter, where we get the chance to spend a few days relaxing with family and friends and enjoying the start of spring. It is traditional at this time of year to give away chocolate Easter eggs, as a symbol of new life. So, for me, the hunt [......

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22.03.2016

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The Top 10 most viewed videos

With over 300 videos available in our YouTube channel you may be overwhelmed on which to watch. So to help we have listed our 10 most popular. Top Ten Videos Principles of Isothermal Titration Calorimetry Zetasizer Nano ZSP – particle size, molecular size, zeta potential &#...

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16.03.2016

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Pittcon 2016 Recap – Lots of interest, and Circus Peanuts too

As you read in previous Pittcon blog posts from Day 1 and Day 2, Pittcon once again provided an excellent opportunity for companies to meet with current and prospective customers to discuss their application challenges and introduce them to their latest technologies. While Pittco...

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15.03.2016

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Elucidating the higher order structure of biopharmaceuticals with DSC

During the development of proteins for use as biopharmaceuticals, the primary structure (amino acid sequence) is important in defining protein activity. Due to the complex nature of protein drugs, compared to small molecule drugs, biophysical techniques are important tools in the...

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09.03.2016

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Day 2 at Pittcon

Don’t forget our remaining short courses Today Separations: Fundamentals of Advanced Gel Permeation & Size Exclusion Chromatography Detection - Ulf Nobbmann Thursday, March 10, 2016 Nanocrystallite and Nanoparticle Size Analysis with an X-Ray Diffractometer - Alan Rawle...

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08.03.2016

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Day 1 at Pittcon

This year Pittcon moved a little NNE from New Orleans, LA, to Atlanta, GA, home of Coca Cola.  According to Wikipedia, Atlanta is considered an “alpha-” or “world city” ranking 36th among world cities and 8th in the nation with a gross domestic product of ...

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03.03.2016

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What is a narrow band filter?

For fluorescent samples (like quantum dots) the Zetasizer has an option that can minimize the effect of (incoherent and thus undesirable for dynamic light scattering) fluorescent light: the narrow band filter eliminates most light that is not very close to the laser wavelength. N...

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01.03.2016

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Missed our February webinars? Catch up here…

As per last month, I compiled the list of On Demand webinars from February. We introduced earlier this year a new webinar program that is focusing on Life Science and Industrial and they already seem to be popular so thank you to you all, Dear Readers! Just pick and choose your f...

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25.02.2016

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Diffusion of (Malvern) Knowledge

I’m reminded of de-sodium-fusion but will avoid this as an opening sentence as it will be understood by but a few chemists……  Ah well, wrong again…. In England, in the early 1800’s, there was a group formed solely for the ‘diffusion of knowledge’.  It was actually more corr...

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24.02.2016

PDF

White Paper: Ein grundlegender Leitfaden zur Partikelcharakterisierung

Grundlagen zu den wichtigsten Verfahren der Partikelcharakterisierung, die derzeit in Industrie und Forschung eingesetzt werden: Theorie der Partikelcharakterisierung und die dafür geeigneten Geräte sowie Kurzreferenz welche Technologie für welche Applikation geeignet ist.

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23.02.2016

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Zetasize at a university near you!

It’s not unusual to see a Malvern Zetasizer in a University laboratory. In fact, there are so many educational institutions taking advantage of the quick and reliable information dynamic light scattering (as well as electrophoretic light scattering) can provide, that it is ...

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19.02.2016

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Application Note: Absoluter Virus-Titers in Minuten

In vielen Fällen müssen Hersteller die Anzahl der Viruspartikel in einem Präparat ungeachtet ihrer Infektiosität bestimmen und das Ausmaß der Aggregation des Präparats als frühzeitiges Anzeichen einer begrenzten Haltbarkeit ermitteln - möglich mit Nanoparticle-Tracking-Analysis.

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18.02.2016

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Isothermal Titration Calorimetry: An essential tool for binding affinity measurements in life sciences research

Isothermal titration calorimetry (ITC) is established in biophysical characterization circles as the “gold standard” for measuring binding affinity interactions involving proteins, lipids, nucleic acids and other biopolymers. Since there are so many ways to measure binding affini...

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16.02.2016

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Spend your spring break with us!

Malvern is offering a two-day course designed to deliver comprehensive knowledge of Malvern’s Viscotek GPC/SEC technologies. The course will be held in Malvern’s Houston, Texas facility from April 13-14, 2016 and will cover the theory behind the advanced detection options of Malv...

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11.02.2016

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Go with the flow – on Pluto….

Rheological – geological – but not mythological… Pluto (not the Disney character – that’s another story) is a word that provokes emotion and comment. This ‘Planet X’ discovered in 1930 by a young graduate student Clyde Tombaugh, never fails to excite the science in all of u...

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11.02.2016

Produkte

Zetasizer zur Messung von Größe, Molekulargewicht und Zetapotenzial bei Nanopartikeln, Kolloiden und Proteinen

Das in diesem Bereich weltweit am weitesten verbreiteten System Zetasizer misst Partikel- und Molekülgrößen von weniger als einem Nanometer bis zu mehreren Mikrometern mit dynamischer Lichtstreuung (DLS); das Zetapotenzial und die elektrophoretische Mobilität mit elektrophore

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09.02.2016

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Helpdesk series – Why are my results out of specification?

As mentioned in my first blog “A day in the life of a Helpdesk Specialist“ in December, I promised to post regularly on the most Frequently Asked Questions we receive in the Support Team. So with that in mind, we will start with - Why are my results out of specificati...

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05.02.2016

Produkte

Der Laserbeuger Mastersizer 3000 zur Partikelgrößenbestimmung

Marktführend, bewährt und etabliert wird Partikelgröße und Volumenverteilung mit dem Malvern Laserbeuger Mastersizer 3000 seit Jahren erfolgreich gemessen.

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04.02.2016

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私は 抹茶と 饅頭が 好きです! (“I like matcha and manju!”)

A vibrant green colour with a slight vegetal smell, this powder is not a sample we commonly receive in the UK application labs.  But then, I am not in the UK. 抹茶は みどりのパウダー です。私は 日本 に すんでいます。 (“The green powder is matcha.  I am living in Japan.”) My “day job” is workin...

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03.02.2016

Veranstaltungen

Fortbildungsseminar: Anwendungsmöglichkeiten der Partikelmesstechnik und Rheologie bei der Herstellung von Suspensionen und ­Emulsionen

22.03.2016 - 23.03.2016

Veranstaltungsort: Fraunhofer-Gesellschaft, Institutszentrum Stuttgart (IZS), Nobelstraße 12, 70569 Stuttgart

Viele Produkte in Lack-/Farbindustrie, Chemie, Lebensmittelindustrie und Pharmazie werden als Suspensionen oder Emulsionen verarbeitet. Dabei sind die Partikeleigenschaften wie Größen- & Formverteilung, das Zetapotenzial sowie die rheologischen Eigenschaften von großer Bedeutung.

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