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24.06.2016

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Ink formulation analysis

Ink formulation screening: Tools for increased throughput I thought I would take this opportunity to share some of the latest data that was collected in one of our laboratories at the Malvern Instruments headquarters in the UK. We have been working with various  batches of blue a...

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23.06.2016

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Mushrooms meet Malvern

Malvern Instruments has made its name in particle sizing: the flagships Mastersizer and  Zetasizer have become the de facto global standard tools for particle sizing from nanometers to millimeters.  The breadth of applications for these technologies is simply astounding and we ar...

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21.06.2016

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From polls to particles: Why is sampling important?

You may have read and have been interested in a recent BBC article dealing with how poll predictions can go badly wrong before an election.  Or you may not: See: Election polls 2015: What went wrong?  http://www.bbc.co.uk/news/uk-politics-35350274 With the upcoming EU referendum ...

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20.06.2016

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Follow that particle!

I’ve always thought it would be great to be the innocent driver in a movie chase scene who has to respond to the hero’s demand to ‘Follow that car’ as they try to keep tabs on the villain. I always imaged that this would unlock the silent racing driver within me, giving me ...

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16.06.2016

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Helpdesk series – The importance of calibrating your Kinexus

Apologies for not posting sooner, but recently I have had the privilege of visiting some of our customers, covering for a service engineer who is temporarily out of action. It is hard work, but it has also been a timely reminder of everything that goes into making sure our instru...

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15.06.2016

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Solvent Peaks – How to get rid of the buffer/salt/additive DLS contribution?

Have you ever seen a peak at small size that you think just should not be there? This can happen under certain conditions, and it is usually due to the signal from the buffer component in the sample. Ultimately, the high sensitivity of today’s dynamic light scattering (DLS)...

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14.06.2016

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FDA highlights Malvern’s innovative MDRS technology for Complex Generic drug product development

Finally!  After what has felt like one of the wettest and longest winters in memory here in the UK, we’re now heading into the long, mellow days of midsummer. But casting its miserable shadow over the barbecues, school holidays and paddling pools is the dreaded allergy season.  A...

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09.06.2016

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Using rheology for faster, smarter formulation

Rheology is often perceived as a theoretical, highly mathematical discipline but in fact it has very practical relevance in defining the behaviour of a wide range of materials including cement, asphalt, cosmetics, foods, paints, inks, blood and much more. Rheology is all around u...

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07.06.2016

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Our Spanish website is live!

Leer este blog en español At Malvern, we are always striving to keep our customers happy, above all else, so we are now delighted to announce the launch of our new website in Spanish! After an incredible amount of translation work, we can finally offer our Spanish-speaking market...

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02.06.2016

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Missed our May webinars? Catch up here…

Hello, once again, I compiled the list of our live webinars that will cover different topics explained by some external presenters. Jonathan Mehtala from Purdue University will explain that Nanoparticle tracking analysis is widely used by viral vaccine and gene therapy. John Gamb...

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01.06.2016

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How the Zetasizer WT helps Canadian’s Water treatment plants

Fort McMurray is a small town in Canada caught in the grip of a natural disaster – a large wildfire burning southwest of the city. More than 100,000 residents of the city and the surrounding area were evacuated. As fire swept towards the city the largest wildfire evacuation...

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31.05.2016

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Microcalorimetry is hot in Brazil!

In February 2016, I participated in microcalorimetry workshops in Rio de Janeiro and Sao Carlos, Brazil. There is a long-standing and active group of calorimetry users in Brazil, and I had the opportunity to give introductory isothermal titration calorimetry (ITC) and differentia...

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26.05.2016

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Adeno-Associated Virus titer and aggregation characterization

We recently published our application note, “Adeno-Associated Virus titer and aggregation characterization“, which discusses a new NanoSight method that allows the visualization and therefore analysis of viruses smaller than what was previously possible to measure.  T...

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25.05.2016

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Upcoming Webinar: John Carpenter discusses silicone oil-induced protein aggregation and immunogenicity

We’re lucky here at Malvern Instruments to have a large number of customers and collaborators who are happy to share their experience of using our technologies for an ever-expanding range of applications.  Some co-write peer-reviewed papers with us, others help us create ap...

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24.05.2016

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Recap of PEGS Boston, the Essential Protein Engineering Summit

I recently had the pleasure of participating in PEGS Boston, the 12th anniversary meeting organized by Cambridge Healthtech Institute (CHI).  The meeting was at Seaport World Trade Center in Boston, Massachusetts, from April 25-29, 2016. I was joined by my Malvern colleagues Bob ...

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19.05.2016

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Malvern at Analytica 2016!

Lesen Sie diesen Blog auf Deutsch GREAT TO MEET YOU! What really matters? Building relationships From the point of view of an exhibitor, exhibitions often mean long days, lots of coffee and sometimes blistered feet if you happen to be wearing the wrong shoes.  Despite this, they ...

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17.05.2016

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The Kinexus gets a manicure…

Over the last few years, the nail polish industry has really opened up its beauty box of tricks, and on the market today, to name but a few, we see nail polishes with “magnetic, gel, matte, glitter, crackle, stamping, quick-dry, caviar, sponge, color changing, leather and sandy” ...

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16.05.2016

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Malvern at AAPS NBC: Zetasize your formulation, VLP, vaccine, and nanoparticle

From nanoemulsions, nanosuspensions, vaccines and adjuvants to drug formulation and release development, this year’s American Association of Pharmaceutical Scientists (AAPS) National Biotech Conference has the strapline: “Advancing health through innovation in biother...

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12.05.2016

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Recap of the 5th International Symposium on Higher Order Structure of Protein Therapeutics

I had the pleasure of participating in the 5th International Symposium on Higher Order Structure of Protein Therapeutics, also known as HOS2016, sponsored by CASSS. The meeting was at the Renaissance Hotel in Long Beach, California April 11-13, 2016. I was joined by my Malvern co...

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10.05.2016

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Missed our April webinars? Catch up here…

Here is another exciting month with some really subject that will be discussed this month again. Here is the full program for May. Register now! As per last month I have compiled the latest list of our On Demand webinars. Just click and choose your favorite subject.    ...

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05.05.2016

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Water treatment – a better way than jar testing?

Water is at the foundation of life. Thus for humans H2O is of critical importance and most directly so for drinking water. In order to prepare water for safe consumption, water treatment procedures have been developed and improved to provide a reliable source of healthy drinking ...

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04.05.2016

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Bioseminar Series 2016 – Addressing Immunogenic Risk

Hello! First I’d like to quickly introduce myself. I just joined Malvern Instruments as a Digital Marketing Specialist based in Westborough, MA, USA office. My main role is to help driving the online and email marketing campaigns. We are pleased to announce our 2016 Bioseminar Se...

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03.05.2016

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Malvern’s Top Content Q1 2016

Malvern Instruments produces a huge array of content, from beginner’s guides to advanced education, all of which is free to access on the Resource Center at Malvern.com. Malvern’s content is available in a variety of formats, and to help explain what these different formats are, ...

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28.04.2016

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Site requirements for the Zetasizer

You are seriously considering ordering a Zetasizer. An excellent choice! A typical email we often receive at this point is: “What are the site requirements for the system?”     The Malvern Zetasizer is a compact benchtop measurement system which requires little space on...

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26.04.2016

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Malvern at Powtech 2016!

Recipe for a successful exhibition: good shoes, good coffee and – most importantly – good conversation! Read this blog in German An exhibition is the perfect platform to discover new products and innovations and to network with key people in related industries who hav...

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21.04.2016

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Elucidation of aggregation kinetics with DLS

“I’m looking to study the aggregation kinetics of my nanoparticles using the Zetasizer Nano ZS. Is there a way to make time-resolved size measurements using this instrument?” The Zetasizer has become a fairly standard sizing tool for nanoparticles, as the size and the size ...

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19.04.2016

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British Science Week 2016

We recently took part in events to celebrate British Science Week, which this year took place over a ten day period from 11th – 20th March. British Science Week is an annual celebration of science, technology, engineering and maths (STEM subjects), with events taking place across...

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14.04.2016

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Team Malvern making moves for charity

We have a wonderful team here at Malvern Instruments, full of people who are constantly looking for ways to give back to the community on a local or even global scale.  And apparently, we are a particularly sporty lot as well, with lots of Malvernites setting out on sponsored run...

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12.04.2016

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Using a Rotational Rheometer for High Shear Rate Measurements

Recently I have been showing some of our rotational rheometer customers how to make high shear measurements on their instruments. This highlights some of the hard to define measurement constraints that rheometer users can have when pushing the practical limits of the instrument. ...

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07.04.2016

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Malvern sponsors 9th Annual Proteins and Antibodies Congress in London

We are proud to be sponsoring the 9th Annual Proteins and Antibodies Congress, to be held at the Novotel London West, UK on 18th and 19th April 2016.  Malvern MicroCal’s Principal Scientist, Dr. Natalia Markova, will be chairing the Protein Expression and Characterization Stream ...

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05.04.2016

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Missed our March webinars? Catch up here…

How time flies! Spring is here already! Just for you I have collated the latest list of our On Demand webinars. Just click and choose your favorite subject. I also listed all our upcoming webinars for April. You can register for free and if you can’t attend, we’ll sen...

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25.03.2016

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Hunting for the Perfect Easter Egg

In the UK we are about to celebrate Easter, where we get the chance to spend a few days relaxing with family and friends and enjoying the start of spring. It is traditional at this time of year to give away chocolate Easter eggs, as a symbol of new life. So, for me, the hunt [......

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22.03.2016

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The Top 10 most viewed videos

With over 300 videos available in our YouTube channel you may be overwhelmed on which to watch. So to help we have listed our 10 most popular. Top Ten Videos Principles of Isothermal Titration Calorimetry Zetasizer Nano ZSP – particle size, molecular size, zeta potential &#...

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16.03.2016

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Pittcon 2016 Recap – Lots of interest, and Circus Peanuts too

As you read in previous Pittcon blog posts from Day 1 and Day 2, Pittcon once again provided an excellent opportunity for companies to meet with current and prospective customers to discuss their application challenges and introduce them to their latest technologies. While Pittco...

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15.03.2016

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Elucidating the higher order structure of biopharmaceuticals with DSC

During the development of proteins for use as biopharmaceuticals, the primary structure (amino acid sequence) is important in defining protein activity. Due to the complex nature of protein drugs, compared to small molecule drugs, biophysical techniques are important tools in the...

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09.03.2016

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Day 2 at Pittcon

Don’t forget our remaining short courses Today Separations: Fundamentals of Advanced Gel Permeation & Size Exclusion Chromatography Detection - Ulf Nobbmann Thursday, March 10, 2016 Nanocrystallite and Nanoparticle Size Analysis with an X-Ray Diffractometer - Alan Rawle...

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08.03.2016

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Day 1 at Pittcon

This year Pittcon moved a little NNE from New Orleans, LA, to Atlanta, GA, home of Coca Cola.  According to Wikipedia, Atlanta is considered an “alpha-” or “world city” ranking 36th among world cities and 8th in the nation with a gross domestic product of ...

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03.03.2016

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What is a narrow band filter?

For fluorescent samples (like quantum dots) the Zetasizer has an option that can minimize the effect of (incoherent and thus undesirable for dynamic light scattering) fluorescent light: the narrow band filter eliminates most light that is not very close to the laser wavelength. N...

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01.03.2016

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Missed our February webinars? Catch up here…

As per last month, I compiled the list of On Demand webinars from February. We introduced earlier this year a new webinar program that is focusing on Life Science and Industrial and they already seem to be popular so thank you to you all, Dear Readers! Just pick and choose your f...

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25.02.2016

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Diffusion of (Malvern) Knowledge

I’m reminded of de-sodium-fusion but will avoid this as an opening sentence as it will be understood by but a few chemists……  Ah well, wrong again…. In England, in the early 1800’s, there was a group formed solely for the ‘diffusion of knowledge’.  It was actually more corr...

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